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Theralpha is a Drug Development Company founded in April 2009 by David Dellamonica, Michel Lazdunski and Marc Vasseur. The goal of the company is to develop differentiated pain therapeutics that can overcome limitations of existing products. The company’s drug candidates are small peptides derived from venoms which exhibit extreme specificity for certain ions channels and which are effective pain killers in animal models. Its pipeline includes 3 candidate drugs: THA901 that targets ASCI1a, THA902 that targets ASIC3, and THA903 with an original although not fully deciphered mechanism of action. THA901 and THA902 have completed pharmacology, and are 12-18 months and 18-24 months ahead of Phase I, respectively. THA903 has completed most regulatory preclinical requirements and will enter Phase I in 9-12 months.

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